Are you seeking a natural way to sharpen your mental focus? Good call. Focus is one cognitive function that can have a tremendous impact on our overall performance. But in today's distracted world, sometimes it's hard to stay present on the task at hand.
Brain supplements called nootropics may to sharpen focus in many different ways. It's challenging, however, to sift through the countless focus supplements on the market today. Many are low-quality. Many more simply don't work for focus... or anything else!
In this article we reveal all you need to know to buy a clean and effective nootropic supplement for focus. We'll cover the best nootropic ingredients and how they work. We'll also recommend high-quality nootropic products that deliver focus benefits and more. Let's get to it!
Key Takeaways
- Focus is the ability to concentrate attention on a specific task or goal, filtering out distractions to maintain sustained mental effort and clarity.
- Nootropics are ingredients in dietary supplements that boost brainpower. They include vitamins, minerals, amino acids, herbs and other nutrients.
- Some nootropics have shown promise in clinical trials to sharpen focus. Others may complement focus with benefits for mental energy, memory, mood, brain health and other areas.
- Many people take nootropics for focus to boost mental performance, especially in high-pressure, attention-demanding like professional settings, academics and sports & fitness.
- Most natural nootropics for focus are considered safe when used as directed. However, individual responses can vary. Always consult with your doctor before starting new supplements.
Nootropics & Nutrients to Consider for Focus Support
- Citicoline: Enhances brain energy, improves focus, and supports overall cognitive function.
- N-Acetyl L-Tyrosine (NALT): Supports focus under stress by replenishing neurotransmitters.
- L-Theanine: Promotes calm focus by increasing alpha brainwaves and relaxing without sedation.
- Phosphatidylserine (PS): Supports multiple aspects of brain health and cognition, including focus.
- Rhodiola Rosea: Reduces stress and mental fatigue, supporting sustained focus and mental clarity.
- Omega-3 Fatty Acids (EPA & DHA): Helps brain health and focus; fights cognitive decline.
- Caffeine: Increases alertness and focus, particularly when combined with L-Theanine.
- Bacopa Monnieri: Enhances attention, working memory, and learning, especially under stress.
- B Vitamins (B6, B9, B12): Support brain health, energy metabolism, and neurotransmitters.
- Maritime Pine Bark Extract: Promotes blood flow to the brain for cognitive performance.
- Essential vitamins & minerals: Zinc, iron, magnesium, B-vitamins (especially B6), Vitamin D and other essential nutrients for brain health have been linked to attentional performance.
- Prebiotics & Probiotics: Optimize gut-brain health, potentially enhancing cognition and mood.
Best All-In-One Nootropic Stack for Focus: Mind Lab Pro®. 11 nootropics in 1 formula that does it all, including boosting focus and attention. Clinically researched, premium and clean. Shop Mind Lab Pro
Best Caffeine Pill for Focus: Performance Lab® Caffeine 2. "Smart caffeine," enhanced with focus nootropics like L-Tyrosine, L-Theanine and B-Vitamins. Precision dose for benefits without jitters. Shop Caffeine 2
Top Nootropic-Driven Pre-Workout for Focus: Pre Lab Pro®. For focus in the gym, this stack is tops. Sport-tuned stimulation plus energy, circulation, intensity and more. Shop Pre Lab Pro
Additional Top Dietary Supplements for Focus
- Performance Lab® Omega-3: Plant-based omega-3s sourced from marine algae. Clean vegan softgels. Easy to take every day, with no fish burps, fish toxins or related eco concerns.
- Performance Lab® Sleep: Sharpens focus via perfect sleep quality. Cherry-sourced melatonin and NutriGenesis magnesium promote deep sleep for daytime focus without grogginess.
- Performance Lab® Prebiotic: Boosts the gut-brain connection, nourishing probiotics in the digestive tract (the microbiome) which can impact dopamine and other brain chemicals.
We'll talk a bit about the best supplement for focus overall right now, and then discuss each of the additional supplements towards the end of this article.
#1 Nootropic Stack for Focus Overall: Mind Lab Pro®
"Universal Nootropic" boosts all types of cognitive function -- especially focus -- in all types of people.
Ingredients: Citicoline, Phosphatidylserine (PS), Bacopa monnieri (24% bacosides), Organic Lion’s Mane Mushroom, Maritime Pine Bark Extract (95% proanthocyanidins), N-Acetyl L-Tyrosine, L-Theanine, Rhodiola rosea (3% rosavins, 1% salidrosides), NutriGenesis® B-Vitamins.
Mind Lab Pro® (MLP®) combines 11 nootropics -- including the best nootropics for focus we cover next -- to optimize multiple brain pathways at once. It's the one nootropic supplement that does all you need: focus, memory, attention, concentration, mood, relaxation, stress resistance, and more.
*MLP® is backed by two double-blind, placebo-controlled human research trials conducted at the University of Leeds have demonstrated Mind Lab Pro®'s cognitive performance benefits.(1,2).
Next up, let's do a deep dive on enhancing focus with nootropics, including details on how the best natural compounds for sharpening your mental clarity work.
What is focus?
Focus refers to the concentration of one's attention to a specific task or topic. Many consider focus to be an important key to mental performance and cognitive wellbeing.
A sharply focused mind may better distinguish audio and visual cues, distinguishing important sensory information from unnecessary distractions. For example, the focused student absorbs the professor's lecture while mentally shunning the sounds of outside play.
- Exceptionally focused thinkers may even compartmentalize sensory input to successfully multitask several assignments at once.
So why does focus falter? Why are so many people researching brain-boosting nootropics as a safe and natural pathway to a clearer, sharper mind?
Some of the reasons why people struggle with their focus include:
- Stress: High stress levels can overwhelm the brain, making it difficult to concentrate on specific tasks.
- Lack of Sleep: Inadequate sleep impairs cognitive processes, reducing the brain's ability to maintain focus.
- Poor Nutrition: A diet lacking essential nutrients can disrupt neurotransmitter balance, leading to diminished focus.
- Distractions: Excessive stimuli from the environment or digital devices can fragment attention, weakening focus.
- Mental Fatigue: Prolonged mental effort depletes cognitive resources, making sustained focus challenging.
- Underlying Health Issues: Conditions like ADHD or anxiety can inherently impair the ability to focus.
- Dehydration: Insufficient hydration reduces brain function, leading to difficulties in maintaining focus.
Certain brain-boosting nutrients can help with each of these concerns. That is why performance-driving natural nootropics for focus are now taking over the game. Let's check out how they work.
How Natural Nootropics May Boost Focus
Altogether, nootropic supplements are suggested to boost focus and overall cognitive performance by:
Optimizing Brain Chemicals: Nootropics influence neurotransmitters like dopamine and acetylcholine, which are crucial for enhancing focus, memory, and overall cognitive function. By supporting the balance and efficiency of these brain chemicals, nootropics help improve mental clarity and focus.
Boosting Brain Energy: nootropics that enhance the brain and body's natural ATP energy production pathways may assist with any number of direct and indirect metabolic cognitive processes, including mental focus and concentration. The higher the concentration demands are required of a given task or assignment, the greater the threat of brain burnout. Optimizing the brain's energy capacity may increase your mental work stamina.
Strengthening Stress Resistance: Aside from high-intensity thinking stress and anxiety may have a significantly negative impact on brain energy and cognitive performance, especially focus. Stress reducing nootropics (or adaptogens) may not only help focus by promoting clear, relaxed thinking.
"Tuning" Brain Waves: Nootropic L-Theanine works by promoting the production of alpha brainwaves, which are associated with a state of relaxed alertness. This helps improve focus, reduce stress, and enhance cognitive performance without causing drowsiness.
Encouraging Blood Flow to the Brain: Nootropics can improve focus by boosting blood flow to the brain, increasing the delivery of oxygen and nutrients to brain cells. This enhanced circulation supports cognitive functions, including attention and mental clarity, by ensuring the brain operates at peak efficiency.
Attention vs. Focus: What's the Difference?
While they go hand-in-hand, there is a subtle difference. Attention is the ability to notice and process sensory information. Focus is the ability to sustain attention on a task or goal, filtering out distractions. For more on the best nootropics for ADHD (attention deficit hyperactivity disorder), specifically, check out our article on the topic here.
Top Nootropics to Consider for Focus
N-Acetyl L-Tyrosine
L-tyrosine is an amino acid nootropic that is important for attention-related brain chemicals. N-Acetyl L-Tyrosine (NALT) is its absorption-enhanced form.
Under conditions of high stress and activity (multitasking, deadlines, sleep deprivation, loud environments), the brain "burns" its natural L-tyrosine reserves to synthesize catecholamine neurotransmitters, such as dopamine, norepinephrine, and epinephrine: focus-related brain chemicals.
Stress-induced catecholamine depletion may lead to brain burnout that hurts mental performance and concentration. Low catecholamine levels have been linked to diminished cognition and attention problems.(3,4)
L-tyrosine supplementation may help.
Researchers have suggested that L-Tyrosine supplementation may help with working memory function, learning speed, mood and cognitive performance while in challenging, distracting and stress-inducing scenarios.(5-8) It is a great nootropic for focus under pressure.
Did you know? Due to B vitamins' co-factor roles in catecholamine conversion pathways, stacking N-acetyl L-tyrosine with B vitamins may further enhance the focus boosting benefits of NALT.
Citicoline
Unlike other sources of choline, Citicoline (also called Cytidine 5'-diphosphocholine or CDP-choline) not only assists with the brain's cholinergic functions but also improvesbrain energy production, a massive benefit to overall brain health and cognitive function, including focus.(9)
Clinical human research has found the Cognizin® brand of citicoline to improve attention, motor speed, and other focus-related performance measures under healthy cognitive conditions.(10)
Did you know? Brain injury may affect focus. Citicoline is considered by some as a leading supplement prospect for brain injury, as it supports brain repair, enhances cognitive function, and improves memory by increasing phospholipid synthesis and boosting acetylcholine levels.
L-Theanine
Amino acid L-theanine seems to work by promoting alpha brainwave frequencies (8-14 Hz), the cognitive state associated with calm, creative thinking; a mental state akin to meditative free-flow. L-Theanine's "wakeful relaxation" helps with focus and chilling out.
This calming compound's focus boost not only prime the mind for a relaxed, productive workday but also eases the mind at bedtime for deep, rejuvenating sleep.
L-Theanine has been widely researched, with some evidence suggesting that it helps to sustain attention and promote relaxation without sedation.(11,12)
L-theanine's ability to sustain caffeine's focus enhancing benefits while minimizing the stimulant's jittery side effects make it even more appealing as a nootropic nutrient.
Maritime Pine Bark Extract
Supplying a natural, rich complex of active proanthocyanidins, maritime pine bark extract seems to possess an antioxidant capacity 20X greater than vitamin E and 50X greater than vitamin C.
In addition to reducing free radical damage, maritime pine bark extract also promotes healthy cerebral circulation, which may further explain the herb's potential to improve on focus and mental performance.
By naturally supporting
More on Maritime Pine Bark Extract
Phosphatidylserine (PS)
Phosphatidylserine (PS) is a great all-round brain booster with many beneficial areas of support. While it is most well-known as the top nootropic for memory, PS may also help to sharpen focus.
It plays a key role in neurotransmitter function, particularly those involved in memory and attention. PS plays a role in brain energy, which is key for mental focus. Researchers also suggest PS may protect the brain from stress and stress hormone cortisol, which may in turn support mental clarity and healthy mood.(13,14)
Additional research has linked daily PS administration for two months to significant improvements in attention performance, short-term auditory memory, working memory, and visual mental performance.
As compared to placebo, daily PS administration for a two month trial period demonstrated significant improvements in attention performance, short-term auditory memory and working memory, and visual mental performance.(15)
Despite a wealth of well-documented research on phosphatidylserine's ability to enhance brain function, researchers have yet to precisely define how PS improves focus and concentration; whether it's through direct or indirect nootropic mechanisms.
PS has also been suggested to improve cognitive performance measures related to concentration, problem solving, language, and communication skills. It's a great add to any nootropic stack.
Rhodiola rosea
This "Golden Root" is associated with the harsh climate of Siberia, where it has been used in folk herbalism for centuries. Rhodiola rosea's strength enables it to grow in harsh conditions.
Likewise, Rhodiola strengthens the person who takes it, assisting with the fight against stress and stress-related brain fog.
Traditionally, Rhodiola rosea was used by Russian farmers to maintain mental clarity and physical vitality through hard workdays in tough environments. The cognitive enhancer was later used in high profile contexts, including by Russian Olympians and Cosmonauts.
Today, researchers believe the herb works by modulating how the body responds to both short-term and long-term stressors. This may be especially significant to anyone seeking effective focus nootropics, since stress can be so devastating to attentional performance.
Rhodiola appears to have research-backed effects that may benefit those with focus problems. Researchers have suggested Rhodiola rosea's stress-busting effects enhance performance and capacity for work (both mental and physical), energize without stimulation or crashing, and promote relaxation and clarity.(16-18)
Bacopa Monnieri
A traditional herbal supplement used in Ayurvedic practices, Bacopa monnieri is considered a nootropic and an adaptogen. That means that it has both brain-boosting and stress response regulating effects -- a potent combination for anyone struggling with attention issues.
Bacopa Monnieri is also among the leading nootropics for memory. Specifically it appears to be a memory multitasker, helping with working memory performance (also called short-term memory, which can be problematic in those with ADHD), new learning, and delayed recall memory.
In one clinical study, researchers said that taking Bacopa supplements every day for 12 weeks helped brain function in many ways, including benefits for memory, recall and learning.(19)
B Vitamins
This B vitamin complex may assist with focus and general cognitive function in a few ways.
One of the most important involves reducing blood homocysteine levels, which may help to improve cerebral circulation. Robust blood flow to the brain is associated with healthy cognitive performance. B-vitamins also help with the production and conversion of focus related brain chemicals.
Three of the most important B-vitamins for focus and general cognitive function are:
- Vitamin B6: Associated with support for brain chemicals including serotonin, GABA, norepinephrine. High-dose B6 has been linked to anti-stress benefits, mood balance and memory support in some human clinical research trials. More on Vitamin B6
- Vitamin B9: Crucial B-vitamin in the fight against out-of-range homocysteine levels; low levels of B9 associated with brain fog. Vitamin B9 is also associated with neurotransmitters dopamine, serotonin and norepinephrine. More on Vitamin B9
- Vitamin B12: Most famous for cell energy, but B12 has other stronger benefits including helping to form the fatty myelin sheaths that surround and protect nerve cells; low B12 levels are associated with age-related cognitive decline. More on Vitamin B12
Lion's Mane Mushroom
Lion's Mane Mushroom has shown potential to enhance focus by stimulating the production of Nerve Growth Factor (NGF, a type of brain derived neurotrophic factor [BDNF]), which supports the growth and maintenance of neurons in the brain.
Lion's mane benefits are attributed to its active nootropics: hericenones and erinacines. The NGF-enhancing benefits of lion's mane mushroom are hard to find in any other dietary supplement and may be profound for overall brain wellness. Specifically, researchers have suggested that:
- Optimal NGF levels nourish and support brain plasticity, neurotransmission, and brain regeneration while protecting healthy brain cells.
- Suboptimal NGF levels, on the other hand, have been linked to mood imbalance, spotty memory function and mildly diminished cognitive function.
Benefits from Lion's Mane NGF support may include enhanced brainpower in those with age-related cognitive decline (mild) and potential improvements for anxiety, mood and brain fog.(20)
In one study on women age 40+, researchers reported that lion's mane mushroom supplementation was associated with significant improvements in mood (depression and anxiety symptoms) and mental concentration. Researchers believe these benefits were not due to NGF enhancement, but rather may be attributed to the other brain-beneficial bioactivities of lion's mane mushroom.(21)
In a more recent clinical study from 2023, researchers reported that lion's mane mushroom hericene A active ingredient appeared to be highly effective in nourishing nerve growth, which in turn may sharpen cognition.(22)
Learn more about Lion's Mane Mushroom
Omega-3 Fatty Acids
Omega-3 fatty acids, particularly EPA and DHA, can help improve focus. Omega-3s play a crucial role in brain health by supporting the structure and function of brain cell membranes, enhancing neurotransmitter function, and reducing inflammation.
Studies have shown that supplementation with omega-3 fatty acids can lead to improvements in attention, particularly in individuals with ADHD and other cognitive disorders. These benefits are believed to result from omega-3s' ability to optimize brain function and support healthy cognitive processes, including focus.
Best Focus Nootropic Supplements to Buy
Mind Lab Pro®
The "Universal Nootropic" to boost all types of cognitive function in all types of people.
Ingredients: Citicoline, Phosphatidylserine (PS), Bacopa monnieri (24% bacosides), Organic Lion’s Mane Mushroom, Maritime Pine Bark Extract (95% proanthocyanidins), N-Acetyl L-Tyrosine, L-Theanine, Rhodiola rosea (3% rosavins, 1% salidrosides), NutriGenesis® B-Vitamins.
Mind Lab Pro® helps to boost brain function in many ways for short-term performance while nourishing long-range brain health. Its 11 nootropics combine to unleash 100% Brainpower: a unique surge of benefits that include ultramodern support for:
- Focus, attention & concentration
- Memory, recall and learning
- Energy and mental alertness (without caffeine)
- Motivation, mood and relaxation
- Sharp mental processing
MLP® is also #1 because it is one of the very few nootropics that is backed by human research:
- Study 1: Subjects taking MLP showed significant improvements (compared to placebo) in information processing tasks.(1)
- Study 2: Subjects taking MLP had significant improvements across multiple memory functions, including auditory, visual, visual working, immediate and delayed recall memory.(2)
Quality is another big reason why MLP® is the top nootropic to buy overall.
- Ultramodern high-quality design: Research-backed nootropic ingredients, focusing on safety, tolerability and effectiveness. Appropriately dosed for benefits without side effects or risks.
- Clean label: No artificial colors, no preservatives, no GMO, no gluten, no caffeine or stimulants, no soy and no synthetic additives. Third-party tested for objective proof of clean quality.
- Vegan-certified ingredients in premium vegan NutriCaps® capsules made from naturally fermented tapioca and infused with prebiotics. No unsafe or synthetic capsule ingredients.
- Eco-Friendly. MLP is B-Corp certified. This designation means that its manufacturer meets stringent standards for ethics and environmentally friendly practices.
Ultimately, Mind Lab Pro® is the one nootropic supplement that does everything you need -- focus, memory, attention, concentration, mood, relaxation, stress resistance, memory and more.
- Get the Best Deal on MLP® Now -
Pre Lab Pro®
“World’s smartest pre-workout drink": smooth energy, focus and peak performance with no jitters or crashes.
Ingredients: Red Beetroot Powder; Setria® Performance Blend; Natural Caffeine; L-Theanine; L-Tyrosine; Vitamin D3, Potassium and Iron (all as NutriGenesis®), Himalayan Pink Salt. Delicious natural berry flavor.
Pre Lab Pro® is a nootropics-enhanced pre-workout formula that emphasizes laser-sharp focus in the gym for amplified performance and maximum gains. It supplies a moderate dose of sport-tuned caffeine with amino acids that balance energy with calm control.
With an additional nitric oxide boost for blood flow plus natural hydration support, Pre Lab Pro® enhances intensity, motivation and mental sharpness throughout your session -- for better gym performance, muscle growth and muscle gains overall.
Performance Lab® Caffeine 2
This "smart caffeine" delivers precision stimulation in a cleaner, healthier format.
Ingredients: Natural Caffeine (from Coffea robusta seeds), L-Theanine, L-Tyrosine, NutriGenesis® Caffeine Balance B-Complex.
If you drink coffee for focus, it's time to try another way: this ultramodern "smart caffeine" pill. Caffeine 2 enhances all caffeine advantages and benefits -- alertness, mental clarity, physical and mental energy -- while reducing jitters, crashes and other unpleasant side effects. The end result is performance-tuned stimulation: Cleaner, healthier, sharper vitality that's easy and convenient to take every day.
More on Performance Lab® Caffeine 2
Performance Lab® Omega-3
Today's most advanced Omega-3 supplement: Ultra-clean and vegan "good fats" sourced from eco-friendly marine algae -- not fish.
Ingredients: Each serving of vegan-friendly, carrageenan-free NutriGels® supplies 1800 mg algal oil (540 mg DHA [Docosahexaenoic Acid]) and 270 mg EPA (Eicosapentaenoic Acid).
Omega-3s are amazing for human health, helping brain function, joint comfort, bone density, eye health, immune performance and more. They also promote bright, balanced mood state that is helpful for focus. The problem? Omega-3s are often sourced from fish. Performance Lab® Omega-3 instead supplies Omega-3s from algae -- not fish -- so you get all those great benefits without "fish burps," gastric distress or concerns about toxic contaminants.
More on Performance Lab® Omega-3
Performance Lab® Prebiotic
Prebiotic fiber feeds gut probiotics (good bacteria) to build a thriving microbiome associated with multiple health benefits.
Ingredients: Each serving of 3 NutriCaps supplies two grams of Inulin-FOS (FructoOligoSaccharides) from chicory root).
Performance Lab® Prebiotic is a performance fiber supplement in convenient capsules. It supports many aspects of wellness, including good digestion, cardiovascular health, immune performance and weight management, as well as “feeding” the microbiome to help support brain chemicals associated with mood and focus. It's the cleanest, most convenient prebiotic supplement on the market today.
More on Performance Lab® Prebiotic
Summary
It's easy to lose focus in modern life that pulls your attention in every direction. But there are many ways to reclaim your focus -- including strategic use of research-backed nootropics.
Mind Lab Pro® supplies some of the best nootropics for focus in premium natural forms, without synthetic "smart drugs" or potential side effects. Supplementing Mind Lab Pro® helps enhance cognitive performance, keeping your mind focused and your eye on the prize.
If you want to maintain sharpness through day-to-day brain fog, age related mental decline, stress or some other cause, you've got more options today than ever before.
Taking a natural brain pill like Mind Lab Pro® is one easy step that can yield impressive focus results. But why stop there?
Consider lifestyle changes to sharpen your focus, as well.
For example, prioritizing sleep can massively impact your daytime attentional performance. Taking a high-quality sleep supplement may help.
Suboptimal intake of some vitamins and minerals can negatively impact mood and mental performance, including focus. For this reason, a multivitamin supplement is also advisable as a foundation for sharp cognitive function.
No matter what approach you take to improving your focus, the natural strategies outlined in this article can help you along the way to success.
Attention, concentration, focus -- all can be reclaimed with the right nourishment and practices, on your way to a peak-performing brain that helps to unlock your full potential.
References
- Utley A, Gonzalez Y, Imboden CA. The Efficacy of A Nootropic Supplement on Information Processing in Adults: A Double Blind, Placebo Controlled Study. Biomed J Sci & Tech Res 49(1)-2023. BJSTR. MS.ID.007746
- Abbott-Imboden C., Gonzalez Y., Utley A. (2023). Efficacy of the nootropic supplement Mind Lab Pro on memory in adults: Double blind, placebo-controlled study. Human Psychopharmacology: Clinical and Experimental, e2872. https://doi.org/10.1002/hup.2872
- Liu L, et al. Simultaneous determination of catecholamines and their metabolites related to Alzheimer's disease in human urine. J Sep Sci. 2011 May;34(10):1198-204.
- Spivak B, et al. Circulatory levels of catecholamines, serotonin and lipids in attention deficit hyperactivity disorder. Acta Psychiatr Scand. 1999 Apr;99(4):300-4.
- Mahoney CR, et al. Tyrosine supplementation mitigates working memory decrements during cold exposure. Physiol Behav. 2007 Nov 23;92(4):575-82. Epub 2007 May 22
- Deijen JB1, Orlebeke JF. Effect of tyrosine on cognitive function and blood pressure under stress. Brain Res Bull. 1994;33(3):319-23
- Thomas JR, et al. Tyrosine improves working memory in a multitasking environment. Pharmacol Biochem Behav. 1999 Nov;64(3):495-500.
- Neri DF, et al. The effects of tyrosine on cognitive performance during extended wakefulness. Aviat Space Environ Med. 1995 Apr;66(4):313-9.
- Silveri, et al. Cognizin® Citicoline Increases Brain Energy (ATP) by 14% and Speeds up Formation of Brain Membranes by 26% in Healthy Adults. Society for Neuroscience, San Diego California
- McGlade E. et al. Improved Attentional Performance Following Citicoline Administration in Healthy Adult Women. Food and Nutrition Sciences. 2012;3:769-773.
- Manuel Gomez-Ramirez, et al. The Effects of L-theanine on Alpha-Band Oscillatory Brain Activity During a Visuo-Spatial Attention Task. Brain Topogr (2009) 22:44–51
- Kimura K. L-Theanine reduces psychological and physiological stress responses. Biol Psychol. 2007 Jan;74(1):39-45
- Monteleone P, Beinat L, Tanzillo C, Maj M, Kemali D. Effects of Phosphatidylserine on the Neuroendocrine Response to Physical Stress in Humans. Neuroendocrinology. 1990;52:243–248.
- Benton D, Donohoe RT, Sillance B, Nabb S. The Influence of Phosphatidylserine Supplementation on Mood and Heart Rate when Faced with an Acute Stressor. Nutr Neurosci. 2001;4:169–178.
- Hirayama S, Terasawa K, Rabeler R, Hirayama T, Inoue T, Tatsumi Y, Purpura M, Jäger R. The effect of phosphatidylserine administration on memory and symptoms of attention-deficit hyperactivity disorder: a randomised, double-blind, placebo-controlled clinical trial. J Hum Nutr Diet. 2014 Apr;27 Suppl 2:284-91. doi: 10.1111/jhn.12090. Epub 2013 Mar 17. PMID: 23495677.
- Hung SK, Perry R, Ernst E. The effectiveness and efficacy of Rhodiola rosea L.: a systematic review of randomized clinical trials. Phytomedicine. 2011 Feb 15;18(4):235-44. doi: 10.1016/j.phymed.2010.08.014. Epub 2010 Oct 30.
- Darbinyan V, Kteyan A, Panossian A, et al. Rhodiola rosea in stress induced fatigue – a double blind cross-over study of a standardized extract SHR-5 with a repeated low-dose regimen on the mental performance of healthy physicians during night duty. Phytomedicine 2000;7:365-371.
- Darbinyan V, Aslanyan G, Amroyan E, Gabrielyan E, Malstrom C, Panossian A. Clinical trial of Rhodiola rosea L. extract SHR-5 in the treatment of mild to moderate depression. Nord J Psychiatry. 2007; 61(5):343-348.
- Morgan A, Stevens J. Does Bacopa monnieri improve memory performance in older persons? Results of a randomized, placebo-controlled, double-blind trial. J Altern Complement Med. 2010 Jul;16(7):753-9. doi: 10.1089/acm.2009.0342. PMID: 20590480.
- Mori K, et al. Improving effects of the mushroom Yamabushitake (Hericium erinaceus) on mild cognitive impairment: a double-blind placebo-controlled clinical trial. Phytother Res. 2009 Mar;23(3):367-72. doi: 10.1002/ptr.2634.
- Nagano M, Shimizu K, Kondo R, Hayashi C, Sato D, Kitagawa K, Ohnuki K. Reduction of depression and anxiety by 4 weeks Hericium erinaceus intake Biomed Res. 2010 Aug;31(4):231-7. doi: 10.2220/biomedres.31.231. PMID: 20834180.
- Martínez-Mármol R, Chai Y, Conroy JN, Khan Z, Hong SM, Kim SB, Gormal RS, Lee DH, Lee JK, Coulson EJ, Lee MK, Kim SY, Meunier FA. Hericerin derivatives activates a pan-neurotrophic pathway in central hippocampal neurons converging to ERK1/2 signaling enhancing spatial memory. J Neurochem. 2023 Jun;165(6):791-808. doi: 10.1111/jnc.15767. Epub 2023 Jan 31. PMID: 36660878.
*These statements have not been approved by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
*This article is an opinion and explanation of current research given by the author. It is not an expression of a medical diagnosis or treatment and should not be relied on as such.